摘要
用同位素掺入法和MTT比色法测定石棉纤维诱导的AM上清液中TNF和IL－6的活性。结果显示，石棉纤维可使AM分泌TNF、IL－6显著增加，其活性明显高于TiO2对照组（P＜0．01），TNF活性最高均值为1198U／ml，IL－6活性最高均值为1511U／ml。
Activities of TNF and IL-6 in AM supernatants induced by asbestos were measured by 3Hthymidine incorperation and MTT tetrazolium salt colorimetric assay. It was found that TNF andIL-6 releases in AM supernatants induced by asbestos increased significantly and were much higherthan those of controls (P＜0. 01). The highest amount of TNF was 1198 U/ml and that of IL-6was 1511 U/ml.
出处
《工业卫生与职业病》
CAS
CSCD
1997年第4期215-218,共4页
Industrial Health and Occupational Diseases
基金
江苏省卫生厅资助
关键词
石棉纤维
肺泡巨噬细胞
肿瘤坏死因子
IL-6
Asbestos
Alveolar macrophage
Tumour necrosis factor (TNF)
Interleukin-6 (IL-6)
