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三氧化二砷联合小剂量阿糖胞苷治疗骨髓增生异常综合征临床观察 被引量:3

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摘要 目的:观察小剂量阿糖胞苷(LD-Ara-C)和三氧化二砷治疗骨髓增生异常综合征(MDS)的疗效。方法:15例患者应用LD-Ara-C10-15mg/m^2.-1次,每12h皮下注射1次,14-21d为1疗程;间隔14-21d重复;三氧化二砷10mg/d。结果:完全缓解4例(26.7%),部分缓解3例(20.0%),例,总有效率46.4%;5例(33.3%)在治疗中或达CR/PR后转为急性白血病,化疗相关病死率6.7%。结论:LD-Ara-C和三氧化二砷治疗MDS有明显疗效且耐受性好。
出处 《临床血液学杂志》 CAS 2008年第1期43-44,共2页 Journal of Clinical Hematology
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