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原发性骨质疏松相关因素的病例对照研究 被引量:1

An case-control study of the relevant factors of primary osteoporosis
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摘要 目的探讨原发性骨质疏松的相关因素。方法选取64例原发性骨质疏松症(OP)患者及68例年龄、性别相均衡的健康对照组,调查内容包括一般情况、血生化检测和肝胆B超检查,对两组进行病例对照研究,分析对照结果。结果单因素非条件Logistic回归分析OP组脂肪肝患病率、高尿酸血症、收缩压、总胆固醇和空腹血糖均显著高于对照组,而总胆红素、直接胆红素、尿素氮显著低于对照组。多因素非条件Logistic回归分析收缩压、直接胆红素、尿素氮和空腹血糖进入回归模型。结论影响骨质疏松的因素很多,为预防和控制OP,应从控制血压、血糖、血脂等多方面相关因素着手。 Objective To discuss the relevant factors of primary osteoporosis. Methods To choose 64 cases of primary osteoporosis (OP) and 68 cases of a health control group with matched ages and sex and investigate general condition, biochemical test and ultrasonographic examination of liver and gallbladder. Then to carry on case-control study of the two groups, to analyze the contrasting result. Results By single-factor non-condition Logistic regression analysis methods, the prevalence of fatty liver, the prevalence of hyperuricemia, systolic pressure, total cholesterol, and blood glucose of empty stomach of the OP group are notably higher than the control group, and total bilirubin, direct bilirubin, urea nitrogen are notably lower than the control group. By multi-factor noncondition Logistic regression analysis methods, systolic pressure, direct bilirubin, urea nitrogen and empty stomach blood glucose enter the regression model. Conclusions There are lots of factors which influence osteoporosis, to prevent and control OP, we should focus on controlling blood pressure, blood glucose, blood lipid etc.
出处 《中国骨质疏松杂志》 CAS CSCD 2008年第2期126-128,共3页 Chinese Journal of Osteoporosis
关键词 原发性骨质疏松 相关因素 病例对照研究 Osteoporosis Relative factors Case-control study
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