摘要
目的探讨分析鼻咽腺癌的临床诊治及预后。方法回顾分析1990年1月-2007年2月间收治16例鼻咽腺癌患者。结果治疗结束后3个月，12例达CR，12例均采取综合治疗，2例达PR（1例单纯切除＋放疗，1例单纯放疗），2例SD其中（1例单纯放疗，1例单纯切除＋放疗）。随诊4．2—90．9个月，平均随访期26．9个月。16例患者均存活，其中12例无瘤存活，4例带瘤存活。在随访期间有2例出现颈淋巴结转移，无1例远处转移。结论鼻咽腺癌进展慢，疾病误诊率高，临床表现以局部症状为主，可出现颈部淋巴结转移，远处转移少见，治疗上以手术为主辅以放疗。
Objective To clinically analyze the diagnosis, treatment and prognosis of nasopharyngeal adenocarcinoma patients. Methods The data of 16 nasopharyngeal adenocarcinoma patients were retrospectively analyzed. There was a significant delay from the onset of symptoms to the time of diagnosis with a range of 2.8 to 38.5 months and a mean time of 11.4 months .9 patients were misdiagnosed before definite diagnosis. The lateral and roof - posterior wall was the most common sites of origin of nasopharyngeal adenocarcinoma which invaded mainly the nasal cavity, the base of the skull . the parapharyngeal space and the longus eapitus. Metastasis to the cervical lymph nodes was observed in 3 cases and 12 patients were comprehensively treated （ B ＋ S 4, B ＋ S ＋ B 2, S ＋ B 6）. Results 1 ） Short- term effect： 12 patients were completely cured 3 months after treatment, 2 partly cured by simple resection plus radiation therapy; 2 with SD（unitary BT1 ,simple resection plus RT 1）; 2） Long- term effect：After a follow- up of 26.9 months （range from 4.2 to 90.9 months）, 16 patients survived （12 without carcinoma, 4 with primary carcinoma, cervical lymphatic metastasis occurred to 2 patients. Distant metastasis was not observed. Conclusion Nasopharyngeal adenocacinoma has long course of progress and the misdiagnosis rate is high. The main clinical manifestations is local symptoms and cervical metastasis might occur and distant metastasis is umcommon. Primaty surgery followed RT was recommended.
出处
《中国热带医学》
CAS
2008年第3期434-435,共2页
China Tropical Medicine
关键词
鼻咽肿瘤
腺癌
诊治
预后
Nasopharyngeal tumor
Adenocacinoma
Diagnosis and treatment
Prognosis
