摘要
目的:评价2%利拉萘酯乳膏手足癣与体股癣的临床疗效及安全性,并与1%联苯苄唑乳膏进行比较。方法:对74例浅部真菌病患者进行治疗,其中治疗组40例,外用2%利拉萘酯乳膏,每日1次;对照组34例,外用1%联苯苄唑乳膏,每日1次。手足癣疗程4周,体股癣疗程2周。分别于停药及停药后2周观察患者的临床表现及治疗效果。结果:2%利拉萘酯乳膏和1%联苯苄唑乳膏临床疗效相似,停药时临床总有效率分别为87.50%和85.29%;停药后2周临床总有效率分别为97.50%和91.17%,两组总有效率比较差异均无统计学意义(P均>0.05),无不良反应。结论:2%利拉萘酯乳膏治疗手足癣和体股癣使用方便,依从性好,安全,有效,是值得推广的一种新型外用抗真菌药。
Objective：To evaluate the efficacy and the safety of liranaftate 2% cream in the treatment of tinea manuum ＆ pedis and tinea corporis ＆ cruris compared with bifonazole 1% cream. Methods：74 cases were divided into 2 groups. The study group （n =40） were treated with liranaftate 2% cream and the control group （n =34） were treated with bifonazole 1% cream, both the cream were topically used once a day. Tinea corporis and tinea cruris were treated for two weeks, tinea manus and tinea pedis were treated for four weeks. Results： The efficacy of liranaftate 2% cream in the treatment of tinea manuum ＆ pedis and tinea corporis ＆ cruris was similar to that of bifonazole 1% cream. The effective rate at the time of finishing the course was 87.50% and 85.29% respectively and was 97.50% and 91.17% two weeks after the treatment, there were no statistically significant differences between the two groups （ P 〉 0. 05 ）. No side - effects were reported in the two groups. Conclusion：Liranaftate 2% cream is effective and safe in treating tinea manuum ＆ pedis and tinea corporis ＆ cruris, could be recommended for treating tinea patients.
出处
《岭南皮肤性病科杂志》
2008年第1期12-14,共3页
Southern China Journal of Dermato-Venereology
关键词
利拉萘酯
手足癣
体股癣
疗效
liranaftate
tinea manuum ＆ pedis
tinea corporis ＆ cmris
efficacy
