摘要
目的对脑型血吸虫病肉芽肿的临床和病理诊断进行分析。方法将患者手术中切除的脑部病变组织,采用快速或常规石蜡包埋切片.HE染色,显微镜下观察脑血吸虫病肉芽肿的病理形态。结果组织切片中见血吸虫病肉芽肿,急性期,中央为新鲜虫卵肉芽肿,周围大量嗜酸性粒细胞浸润,形成嗜酸性肉芽肿。慢性期为退变虫卵,其外为增生的胶质细胞,上皮样细胞和异物巨细胞,形成假结核样结节,以及纤维组织增生、胶元化。结论血吸虫病肉芽肿是脑型血吸虫病临床表现的病理基础,以血吸虫卵为中心形成的肉芽肿病变,是脑型血吸虫病的主要病理学形态特点。
Objective To analyze the clinical and pathological diagnosis of cerebral schistosomal granuloma. Methods Tissue from patients with cerebal schistosomal granuloma was pathologically analyzed by paraffin section, HE staining and observed by microscope. Results Schistosomal granuloma was seen in the tissue section. Within the acute phase central of the tissue section was fresh insect egg granuloma, and around of it were plenty of eosinophil infiltration, epithelioid cells and pseudotubereles formed by gaint cells. In the chronic phase were degenerated eggs,and around of it were hyperplastic keratinocytes proliferation,epithelioid cells and gaint cells formed pseudotubercles and hyperplastic fibrous tissue. Conclusion Schistosomal granuloma is the pathological base which causes the clinical manifestations of cerebral schlstosomiasis and the granuloma with schistosomal eggs in the center is the main patho-logic character of cerebral schistosomiasis.
出处
《中国基层医药》
CAS
2007年第12期2022-2024,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
血吸虫病
脑型
肉芽肿
临床表现
病理诊断
Sehistosomiasis
Cerebral
Granuloma
Clinical manifestations
Pathological diagnosis
