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CXCL12-CXCR4生物学轴在肿瘤侵袭与转移中的研究进展 被引量：2

The advances of CXCL12-CXCR4 biological axis in tumor invasion and metastasis
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摘要 研究发现多种肿瘤细胞表达趋化因子CXCL12及其受体CXCR4，并与肿瘤细胞的迁徙和转移密切相关；CXCL12-CXCR4生物学轴在多种肿瘤的播散和器官特异性转移中发挥重要作用。 Researches indicated that various tumor cells could express chemokine CXCL12 and its receptor CXCR4, which were closely related to migration and metastasis of tumor cells. The biological axis of CX- CL12-CXCR4 played an important roles in migration and metastasis to specific organs in various tumors.
作者 吕明(综述) 赵文华(综述) 李胜(审校)
机构地区 山东省淄博市中心医院骨科 山东省肿瘤医院肝胆外科 不详
出处 《国际肿瘤学杂志》 CAS 2008年第2期90-92,共3页 Journal of International Oncology
基金 国家自然科学基金资助项目（30600603） 山东省优秀中青年科学家科研奖励基金资助项目（2005BS03003） 山东省医药卫生科研基金资助项目（2005HW-133）
关键词 趋化因子类 肿瘤转移 Chemotactic Factors Neoplasms metastasis
分类号 R730.21 [医药卫生—肿瘤]
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共引文献26

同被引文献21

  • 1苏一乐,宋静慧,吉亚南.子宫颈癌和盆腔淋巴结组织中趋化因子受体CXCR4及其配体CXCL12基因DNA的表达及其意义[J].中华妇产科杂志,2006,41(10):717-719. 被引量：8
  • 2霍志军,陈道瑾,李小荣,唐利立,吴唯.乳腺癌和纤维瘤中RECK-mRNA和MMP9-mRNA的表达差异及意义[J].中国普通外科杂志,2007,16(1):69-72. 被引量：5
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  • 10Phillips RJ,Burdick MD,Lutz M,et al.The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-smallcell lung cancer metastases[J].Am J Respir Crit Care Med,2003,167(12):1676-1686.

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二级引证文献9

国际肿瘤学杂志
2008年 第2期

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