摘要
目的:研究年龄同素对急性胰腺炎的病理类型及预后的影响。方法:采用Blamey多指标预测评分体系,对319例急性胰腺炎按年龄≤55和>55岁分组,结合经外科、CT或腹穿证实的坏死型和水肿型胰腺炎统计分析.结果:>55岁组的坏死型急性胰腺炎的比率与Blamey指标的积分均高于<55岁组;计数相关及直线相关分析均示年龄与急性坏死性胰腺炎呈正相关(rn=0.33,P<0.005;r=0.57,P<0.001);>55岁组中与急性胰腺炎有关的9种发病因素中,胆石症及高脂血症多于≤55岁组;92例坏死型胰腺炎10种106次并发症中,88例次(83%)分布于>55岁者;死亡32例中,27例(84%)年龄>55岁;8种年龄界值的判别价值示>55岁及>60岁二者对坏死型的敏感性、特异性和预测准确性较高。结论:取值>55岁作为急性胰腺炎的高危指标单独或列入一个预测体系较为合理。
Objective: To investigate the influence of age on the pathological types and prognosis of acute pancreatitis. Method: Blamey's multifactorial prognostic scoring system was employed in 319 patients with acute pancreatitis grouped according to their ages (≤55, >55) andanalysed statistically on the basis of pathological types (necrotizing or edematous) confirmed bysurgery, computered tomography or peritoneal punctures. Results: Both the numbers of acute necrotizing pancreatitis (ANP) and scores of Blamey's system were higher in>55 group than in ≤55 group; positive correlations (rn=0.33, P<0.005; r=0.57, P<0.001) were found between the age and ANP either in enumeration or in rectilinear correlation analysis; among the conditions associated with acute pancreatitis, incidence of cholelithiasis and hyperlipidemia were higher in >55 than in≤55 group; of the 106 complications of 10 kinds in 92 cases with ANP, 88(83%) were seen in those older than 55 and 27 of 32 cases (84%) died were older than 55; two of 8 age-groupingparameters, namely, >55 and>60, showed better sensitivity, specificity and correct prediction thanthe others. Conclusion: It is quite reasonble to adopt age>55 as the sole high-risk parameter or in a prognostic system in the assessment of the severity of acute pancreatitis.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1997年第2期100-102,共3页
Chinese Journal of Digestion
关键词
急性
胰腺炎
诊断
预后
Acute pancreatitis,Diagnosis,Prognosis