摘要
目的:探讨艾司西酞普兰治疗抑郁症的疗效及安全性。方法:将63名抑郁症患者随机分为两组,分别给予艾司西酞普兰和马普替林治疗,疗程6周。采用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表病情严重程度(CGI-SI)、治疗中出现的症状量表(TESS)评定疗效及不良反应。结果:艾司西酞普兰与马普替林治疗抑郁症疗效相当,但艾司西酞普兰起效更快,不良反应更少。结论:艾司西酞普兰治疗抑郁症安全有效。
Objective： To detect the et-ficacy and side effects of escitalopram in the treatment of depresssion. Method：63 patients with depression were divided into escitalopram group or maprotiline group respectively for 6 weeks. Hamilton depressive scale （HAMD）, clinical global impression severity of illness （CGI-SI） and treatment emergant symptom scale （TESS） were used to evaluate the efficacy and side effects before and after the treatment. Results：There was no significant difference in the efficacy between these two groups. Escitalopram took effect more quickly and less side effects than maprotiline. Conclusion： Escitalopram is a safe and effective antidepressant.
出处
《临床精神医学杂志》
2008年第1期49-50,共2页
Journal of Clinical Psychiatry
