摘要
研究了散瘀胶囊的制备工艺,并对其关键步骤如加水量、煎煮时间、煎煮次数、醇沉浓度等条件进行优选,确定最佳工艺。对本制剂的质量标准进行方法学研究,以CS-9000型薄层扫描仪检测,摸索出主药大黄中有效成分大黄素的提取分离及薄层展开条件,回归方程A=66869.272C+9621.037,γ=0.9975,回收率96.91％,RSD=3.11％。
Manufacturing process of San Yu capsule was studied and the main technological parameters were decided, including water volume, decocting hours,decocting times and concertration of alcohol sediment. Then, TLC method was used to determine the content of emodin,which was the effective ingredient in this preparation. Its regression equation was .A = 66859. 272r + 9621. 037,the related coefficient was 0. 9975, the precentage of recovery was 96. 91% and the coefficient of variation was 3. 11%.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1997年第3期142-145,共4页
Journal of China Pharmaceutical University
关键词
散瘀胶囊
制药工艺
中成药
San Yu capsule
Orthogonal experiment design
Emodin
Thin layer scanning.
