乳杆菌治疗细菌性阴道病的临床研究被引量：2

Lactobacillus in Treatment of bacterial vaginosis:A Clinical Study

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摘要目的探讨乳杆菌在治疗细菌性阴道病(BV)中的作用。方法将确诊为BV的120例患者随机分成3组,单纯使用甲硝唑者(A组)40例,联合使用甲硝唑及乳杆菌者(B组)40例,单纯使用乳杆菌者(C组)40例。对3组患者的临床症状及实验室检查结果进行分析。结果3组患者治疗后第1次复诊时A、B组患者的疗效间差异无统计学意义(P<0.05),C组患者的疗效与A、B组间差异有统计学意义(P<0.05);第2次复诊时3组患者的疗效间差异有统计学意义(P<0.05)。结论在治疗BV时,应首先应用甲硝唑,感染控制后再使用乳杆菌恢复阴道内正常菌群环境,可以取得较好的治疗效果。 Objective To probe into the curative effects of lactobacillus on bacterial vaginosis （BV）, Methods 120 cases with BV were divided randomly into 3 groups. Group A （ n = 40） were treated with metronidazole, Group B （ n = 40） with metronidazole combined with lactobacillus; Group C （n = 40 ） with lactobacillus. Respectively on the 14th and 30th days after treatment, we compared the curative effects among the three groups. Results The curative effects of Group A and Group B were better than that of Group C on the first visit （on the 14th day）（82. 5% , 84. 6% VS 56.4% ; P 〈 0, 05） ; On the second visit （on the 30th day） , there was significant difference in curative effect among the 3 groups （79. 1% , 87.5% , 68.2% , P 〈 0.05）, Conclusion It is concluded that in the treatment of BV, metronidazole should be used first, and lactobacillus can be used to improve the endovaginal micro -organism environment when infection is controlled.

作者曹翠娟刘朝晖

机构地区河北省石家庄市正定县人民医院妇产科北京大学第一医院妇产科

出处《中国全科医学》 CAS CSCD 2008年第4期337-338,共2页 Chinese General Practice

关键词乳杆菌阴道病细菌性甲硝唑 Lactobacillus Vaginosis, bacterial Metronidazole

分类号 R711.31 [医药卫生—妇产科学]

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参考文献5

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