摘要
为探讨耳蜗负和电位与动作电位(-SP/AP)比值变化与膜迷路积水的关系,测试44例Meniere病(病侧59耳,健侧29耳)和52例非Meniere病(半面痉挛24例,三叉神经痛28例;病侧53耳,健侧51耳)的耳蜗电图。结果Meniere病组病侧耳的-SP/AP比值与同组健侧耳、非Meniere病组病侧耳及健侧耳的-SP/AP比值相比都明显升高(P<0.001)。22例Meniere病还做了甘油试验,结果纯音听力甘油试验阳性率为56.3％,耳蜗电图甘油试验阳性率为81.3％,服甘油后比服甘油前-SP/AP比值显著下降(P<0.001),表明-SP/AP比值变化与膜迷路积水程度有密切关系。行耳蜗电图检查及甘油试验,有助于Meniere病的诊断和确立治疗方案。并对耳蜗电图检查及甘油试验的机理及少数变异结果进行讨论。
To explore the ratio of negative summating potential (-SP) to action potential (AP) in cochlea and hydrolabyrinth,electrocochleogram(ECochG)was detected in 44 patients with Meniere disease (59 diseased and 29 healthy ears)and 52 non-Meniere disease patients (including 24 cases with semi-facial spasm and 28 cases with trifacial neuralgia,53 diseased and 51 healthy ears). The results showed that the -SP/AP value on patient's diseased ears of MD was significantly higher than that of patient's healthy ears of MD and patient's diseased and healthy ears of non-Meniere disease(P<0. 001). Glycerol Test(GT)was performed in 22 patients with MD. According to selfestablished standard, positive rates of PTA and -SP/AP value in diseased ears was 56. 3% and 81. 3% .respectively. -SP/AP value of diseased ears remarkably decreased after taking glycerol(P<0. 001) ,but in healthy ears, there was no significant difference in -SP/AP value before and after taking glycerol(P>0. 05). The results suggested that there was a close relationship between changes of -SP/AP value and degree of hydrolabyrinth. E-CochG and GT were helpful for the diagnosis and the selection of treatment measures of MD. The different results of GT were analyzed and discussed in detail.
出处
《天津医药》
CAS
1997年第7期399-402,共4页
Tianjin Medical Journal
关键词
耳蜗电图
膜迷路积水
甘油试验
electrocochleogram hydrolabyrinth glycerol test Meniere disease
