摘要
介绍了两种纯制百日咳杆菌丝状血凝素的方法,并对不同方法纯化的丝状血凝素的产量、纯度、生物学活性等方面进行了比较,从中选择出一种纯度高、活性好、可以大批量提纯的方法。
Two different methods of purifing FHA from Bordetella Pertussis culture were investigated.The results showed that the purity,recovery rate,and characterization of FHA purified by method Ⅱ is suitable to the reference for quality control of acellular pertussis vaccine.
出处
《微生物学免疫学进展》
1997年第2期12-16,共5页
Progress In Microbiology and Immunology
关键词
百日咳杆菌
丝状血凝素
制备
生物学特性
Filamentous hemagglutinin Chromatography Bordetella pertussis