摘要
O，O-二烷基硫酮代磷（膦）酸酯（3）与三氯氧磷发生异构化氨化反应得到S-烷基硫代磷（膦）酰氨（4），4与2，6-二氯-4-取代苯酚反应，合成了26种新的标题化合物．生物活性初步测定结果表明，这些化合物均有一定的杀菌活性．
S-Alkyl thiophosphoro (-phosphono-)chloridates 4 were prepared by the isomer-ization/chlorination reaction of O,O-dialkyl thiophosphates(-phosphonates) 3 with phospho-rus oxychloride- The isomerization/chlorination of 3 containing bulkier R and R1 groups re-quire higher reaction temperatures and Ionger reaction time. 4 reacted with 2, 6-dichloro-4-substituted phenols to give 26 new target compounds 6, which were tested in vitro against many fungi such as P. Zeae, P. Piricola, R. Solani, A- Solani and D. Arachidicala, etc. The bioassay results show they have some fungicidal activity.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1997年第1期55-59,共5页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
