摘要
背景与目的:上皮样肉瘤是一种少见的软组织肉瘤,多表现为肢体远端的结节或溃疡性病变,可通过腱鞘局部播散、淋巴道和血道转移。因其切除后易复发转移、有较高的淋巴结转移率而区别于其他的软组织肉瘤。本文通过分析上皮样肉瘤临床特点,治疗效果,生存情况,预后因素,旨在探讨其治疗方法及预后的影响因素等。方法:回顾我院1999-2007年收治的获得随访的18例上皮样肉瘤,对其临床表现、淋巴结转移、治疗情况、生存率及预后进行分析。结果:上皮样肉瘤5年生存率为41%,局部复发率为44.4%。即使截肢,术后仍有复发。在11例行淋巴结清扫的患者中淋巴结转移率为63.6%。结论:上皮样肉瘤是一种侵袭性较强、淋巴结转移率高、术后易复发的软组织肉瘤,手术应充分考虑切除的广泛性。
Background and purpose： Epithelioid sarcoma is a rare histological subtype of sarcoma. The tumor frequently appears as a nodular or ulcerated lesion on a distal extremity. This tumor can extend regionally along tendon sheaths and spread through lymphatics and vascular channels. The high local recurrence rate and incidence of nodal metastases differ epithelioid sarcoma from other types of sarcoma. The aim of this study was to evaluate treatment and prognostic factors of epithellold sarcoma. Methods： The clinical manifestation, lymph node metastasis, treatment, survival rate, prognosis of 18 cases of the epithelioid sarcoma in limbs were reviewed. All 18 cases were treated and followed up in our hospital from 1999 to 2007. Results： The 5-year survival rate was 70% . The local recurrence rate was 44.4%. The lymph node metastasis rate was 63.6% in 11 cases who had been treated with lymphadenectomy. Conclusions： Epithelioid sarcoma is a very aggressive form of soft-tissue sarcoma, with high rates of local recurrence and a propensity to lymph node metastases. Extensive resection should be fully considered during operation.
出处
《中国癌症杂志》
CAS
CSCD
2008年第1期11-14,共4页
China Oncology
关键词
上皮样肉瘤
软组织肉瘤
诊断
预后
epithelioid sarcoma
soft tissue sarcomas
diagnosis
prognosis
