摘要
按照全国铅中毒诊断标准修订协作组统一质控规范，对陕西地区铅中毒进行了一次职业流行病学调查．调查了铅接触组275名，对照组194名。取得了陕西地区有质量保证的血铅、尿铅、ZPP、EP与ALA的正常参考值。结合调研结果，对常用铅中毒实验室检测指标进行了评价．并用Bayes判别分析法得出了各项指标的三值（正常值、可接受上限值与诊断值）。将所得三值与全国协作组建议值及其他协作地区所得之三值进行了对比，多数较吻合。从而对全国协作组提出的建议值进行了客观验证。
According to the quality control program of nationwide cooperative study, 275 lead exposed workers had been studied in Shanxi area, and 194 healthy persons without lead exposure served as a reference group. The quality assurance 'normal reference value' of lead in blood (PbB), lead in urine (PbU), erythroprotoporphyrin (EP) and zinc protoporphyrin (ZPP) in blood, and δ-ALA in urine (ALA) had been acquired in this area. Based on the materials of the study, an evaluation of different lead biological indexes had been done. By using discriminant analyses with Bayes formula, the'three values ' (normal reference value, biological exposure limit value, and diagnostic lower limit value) were obtained. Compared those three values with those recommended by national cooperative group, and those acquired from another area in this nationwide study, it was found that most of them were similar, and proved that the three values recommended by national cooperative group were reasonable in China.
出处
《广东微量元素科学》
CAS
1997年第5期24-28,共5页
Trace Elements Science
关键词
铅中毒
诊断
实验室检测指标
Lead poisoning, Diagnosis of lead poisoning, Biological monitoring index of lead poisoning
