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冠心病患者肱—踝脉搏波传播速度的临床研究 被引量:6

Clinical study of brachial-ankle pulse wave velocity in patients with coronary heart disease
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摘要 目的探讨冠心病患者动脉僵硬度的改变。方法128例行冠状动脉造影的患者,在同期内(间隔<1个月),采用动脉硬化测定仪Colin测定肱-踝脉搏波传播速度(baPWV)。结果冠状动脉造影阳性组baP-WV为(1701±305)cm/s,冠状动脉造影阴性组为(1482±184)cm/s,冠状动脉造影阳性组较阴性组baPWV值显著增高(P<0.05):冠状动脉病变1支组baPWV为(1730±280)cm/s,2支组baPWV为(1684±313)cm/s,3支组为(1690±165)cm/s,均较冠脉造影阴性组baPWV值显著增高(P<0.05),不同冠状动脉病变支数组之间baPWV值差异无统计学意义(P>0.05)。结论冠心病患者动脉僵硬度增高,baPWV增高,baPWV可作为冠心病危险的预测因子之一。 Objective To determine the change in arter,stiffness in patients with coronary heart disease (CHD). Methods One hundred and twenty-eight patients who underwent coronary angiography (CAG) were subjected to a contemporary measurement (within one month from CAG) of braehial-ankle artery pulse wave velocity (baPWV) using a Colin system. Results The baPWV value was (1701±305)cm/s in CAG (+) group vs (1482±184)cm/s in CAG (-) group (/)〈0.05). The baPWV values in those with 1, 2 or 3 coronary branches involved were (1730±279)cm/s, (1684±313)cm/s and (1690±165)cm/s respectively; although not significantly different among these subgroups (P〉0.05), these values were higher than those found for CAG(-) group (P〈0.05). Conclusion The baPWV value was shown to increase with artery stiffness in coronary heart disease, suggesting its potential use as a predictor of risk for CHD.
出处 《中国药物与临床》 CAS 2008年第2期93-95,共3页 Chinese Remedies & Clinics
关键词 冠状动脉疾病 动脉硬化 肱-踝脉搏波传播速度 Coronary disease Arteriosclerosis Stiffness Braehial-ankle artery pulse wave velocity
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