摘要
目的探讨桂哌齐特联合舒血宁治疗急性脑梗死患者的临床疗效。方法将脑梗死患者按入院顺序随机分为治疗组和对照组,治疗组用桂哌齐特联合舒血宁,对照组用葛根素注射液进行临床疗效比较并动态测定血浆CRP、ET和NO浓度。结果桂哌齐特和舒血宁联合应用治疗急性脑梗死的临床显效率及神经功能缺损程序评分明显优于对照组(P<0.01)。治疗组CRP、ET及NO在治疗后与对照组相比均有统计学意义。在治疗后14d与对照组比较CRP、ET及NO均明显改变(P<0.01)。结论桂哌齐特联合舒血宁治疗急性脑梗死临床疗效显著,安全实用。
Objective To observe the therapeutic effects of cinepazide maleate and shuxuening in treatment of a- cute cerebral infarction. Methods Seventy - six patients with cerebral infarction were divided randomly into 2 groups ： The experimental group （ n =38） treated with cinepazide maleate（320 mg a day） and shuxuening （20 ml a day） for 14 days;The control group （n = 38 ） treated with puerarin （400 mg a day） for 14 days. Plasma C - reactive protein （CRP）, endothelia （ET） and nitric oxide （NO） levels, ET ang NO were detected before the treatment and at the 14th day. Results The effects of cinepazide maleate and shuxuening was better in treatment group than that in the control group （P 〈 0.01 ）. The levels of plasma ET and CRP decreased significantly at the 14th day. No levels increased significantly at the 14th day（ P 〈0.01 ） in control group. Conclusions The results indicates that the efficacy of cinepazide maleate and shuxuening in treatment of acute cerebral infarction is better than that treated with puerarin.
出处
《医学信息（手术学分册）》
2007年第11期967-969,共3页
Medical Information Operations Sciences Fascicule
关键词
脑梗死
急性
桂哌齐特
舒血宁
C-R应蛋白
内皮素
一氧化氮
cerebral infarction
puerarin
cinepazide maleate
shuxuening
C - reactive protein
endothefin
nitric oxide
