摘要
为探讨上海地区庚型肝炎病毒感染的现状，采用逆转录套式聚合酶链反应（ＲＴＮｅｓｔｅｄＰＣＲ）检测庚型肝炎病毒（ＨＧＶ／ＧＢＶＣ）核酸（ＨＧＶＲＮＡ）。结果在各类患者和助血员中ＨＧＶＲＮＡ的检出率分别是：血液透析和肾移植为１５７％（８／５１）、丙型肝炎为３３％（１／３０）、乙型肝炎为０（０／１９）、散发性非Ａ～Ｅ型肝炎为０（０／２８）、义务助血员为７５％（５／６７）。提示ＨＧＶ感染多为无症状或亚临床型，常与ＨＣＶ重叠感染，并与输血密切相关。作者肯定了上海地区存在庚型肝炎，指出筛选助血员对控制输血后庚型肝炎至关重要。
In order to study hepatitis G virus (HGV) infection in Shanghai,Nested RT-PCR has been established to detect RNA of HGV/GBV-C according to literature.Results showed the positive detection rate was 15.7%(8/51),3.3%(1/30),0(0/19) and 0(0/28) in patients with hemodialysis or kidney transplation,hepatitis C,hepatitis B and hepatitis Non A-E respectively as well as 7.5%(5/67)of blood donors were found positive for HGV/GBV-C RNA..The clinical manifestation of HGV infection was generally mild or subclinical.HGV infection had a close correlation with blood transfusion and may be coinfected with HCV.There was a high infection rate among blood donors.The existence of HGV infection in Shanghai could be affirmed and it is suggested that screening blood donors is of prime importance for the prevention of post-transfusion bepatitis G.
出处
《中华传染病杂志》
CSCD
北大核心
1997年第3期142-144,共3页
Chinese Journal of Infectious Diseases
关键词
庚型肝炎病毒
聚合酶链反应
核酸杂交
输血
Hepatitis G virus
Polymerase Chain Reaction
Nucleic acid hybridization
