摘要
使用微型呼气峰流速（PEF）仪测定了1394例重庆地区健康人的PEF值，建立了正常回归方程式。在此基础上，我们测定了134例哮喘患者的PEF，并计算出哮喘患者PEF占正常预计值的百分比。以上患者单纯按哮喘的临床症状的严重度分为：轻度，中度和重度哮喘。结果表明PEF占预计值的百分比随哮喘的严重增加而降低，各组之间差异显著，提示PEF在一定程度上可以反映哮喘的严重度。但依临床表现和PEF两种哮喘严重度分级并不完全一致。轻度和重度哮喘组与PEF分级的吻合率较高，分别为71．4％和74．5％。而中度哮喘组的吻合率则较低，仅为52．9％。本文结果提示，单纯用临床表现进行哮喘的严重度分级将导致相当多的病入分级错误。其中20．9％的病人被低估病情。正确的评估哮喘的严重度应尽可能测定肺功能。
A classification of asthma based on severity is of importance when decisions have to be made about the treatments in the stepwise approach recommended by Global lnitiative for Asthma (GINA ). The regressional formula of peak expiratory flow(PEF) was set up on thd basis-of determination of 1394 tealthy non-smoker persons in Chongqing area by miniWight PEF meters. 134 patients with asthma were classified into mild,moderate and severe grade by their symptoms under the criteria on made by Chinese Respirology Association and their PEF were rneasured in remission. By the percentage of prediction PEF of the measured readings≥80%,60~80% or≤60%,the patients also were classified into mild,moderate and severe grades respectively. The results show that two of classifications were not completely identical.71. 4% mild and 74. 5% severe patients with asthma classifield by symptoms had same grade as classification by PEF measurement. But only 52. 9 % moderate patients was consistent with grade by PEF methods. In conclusion,appropriate classification of asthma severity should be on the basis of measurement of symptoms and PEF or conventional lung functions. Otherwise,some of patients'severity will be underestimate.
出处
《重庆医学》
CAS
CSCD
1997年第5期261-262,共2页
Chongqing medicine
关键词
哮喘
呼气峰流速
分级
asthma, peak expiratory flow,grade
