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厄贝沙坦与福辛普利联合用药对高血压病的疗效及左心室舒张功能的影响 被引量:8

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摘要 目的:探讨厄贝沙坦和福辛普利联合用药的降压疗效及对左心室舒张功能的影响。方法:将113例原发性高血压病患者随机分为3组:厄贝沙坦组35例,150mg/d;福辛普利组37例,40mg/d;联合用药组41例,厄贝沙坦150mg/d与福辛普利20mg/d。疗程18个月。记录血压,检测治疗前、后左心室舒张功能的变化。结果:与治疗前比较,各治疗组均能降低血压,改善左心室舒张功能,且联合用药组较单独用药组疗效更好。结论:厄贝沙坦和福辛普利联合用药显著降低血压,改善左心室舒张功能,比单独用药效果明显,且不良反应较少。
出处 《中国医药导报》 CAS 2008年第3期70-71,共2页 China Medical Herald
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  • 1[1]Orozco-Valero M. Large therapeutic studies in elderly patients with hypertension [J]. J HumHypertens, 2002, 16 (1): 38.
  • 2[3]Kokkinos PF, Andreas PE, Coutoulakis E, et al. Determinants of exercise blood pressure response in normotensive and hypertensive women: role of cardiorespiratory fitness [J]. J Cardiopulm Rehabil,2002,22(3):178-183.
  • 3[6]Blumenfeld JD, Sealey JE, Mann S J, et al. Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the reninangiotensin-aldosterone system in normotensive and hypertensive subjects [J]. Am J Hypertens, 1999, 12 (5): 451.
  • 4[7]Tedesco MA, Di Salvo G, Ratti G, et al. Left atrial size in 164 hypertensive patients: an echocardiographic and ambulatory blood pressure study [J]. ClinCardiol, 2001, 24 (9): 603-607.
  • 5[8]Malfatto G, Branzi G, Riva B, et al. Recovery of cardiac autonomic responsiveness with low-intensity physical training in patients with chronic heart failure [J]. Eur J Heart Fail, 2002, 4 (2):159-166.
  • 6[9]Allen AM, Zhuo J, Mendelsohn FA. Localization and function of angiotensin AT1 receptors [J]. Am J Hypertens, 2000, 13 (1Pt 2): 31s-38s.
  • 7[1]Smith RD, Timmermans PB. Human angiotensin receptor subtypes [J]. Curr-opinNephol-Hypertens, 1994, 3 (1): 112-122.
  • 8[3]Oparil S, Bar E, Elkins M, et al. Efficacy, tolerability and effects on quality of life of losartan,alone or with hydrochloroth iazide, in patients with essential hypertinsion[J]. Clin Ther, 1996,18: 608.
  • 9[5]Kassler TK, Little JT, Elliott W, et al. Comparative efficacy of two angiotensin Ⅱ receptor antagonists, irbesartan and losartan in mide-to-moderate hypertension, lrbesartan/losartan study Investigators [J]. Am J Hypertens, 1999, 12: 79-81.
  • 10[7]Pitt B, Segal R, Martinez FA, et al. Randomised trial of losartan versus captopril in patients over 65 with heart failure [J]. Lancet,1997, 349: 747-752.

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