摘要
[目的]探讨江苏省恶性肿瘤低发地区主要肿瘤有关危险因素。[方法]在江苏省恶性肿瘤低发的赣榆地区进行了以人群为基础的肿瘤1∶1配对病例对照研究,应用条件Logistic回归对相关因素进行单因素和多因素分析。[结果]食管癌和胃癌的共同危险因素为进食快(OR食管=1.95,OR胃=1.46)、热烫饮食(OR食管=2.72,OR胃=2.21)、癌症家族史(OR食管=2.02,OR胃=2.29);对于肺癌而言,吸烟越早(OR=3.63)、烟龄越长(OR=4.13)、吸进部位越深(OR=2.79)均能增加患病概率;饮茶是食管癌(OR=0.73)、胃癌(OR=0.37)、肺癌(OR=0.60)和肝癌(OR=0.27)的共同保护因素,而生吃大蒜对食管癌(OR=0.68)和胃癌(OR=0.64)的保护作用比较确切。[结论]本次研究所发现的有关结果可以为江苏省肿瘤低发及高发地区的防治工作提供参考。
[Purpose] To explore the common risk factors of cancer in low cancer incidence area in Jiangsu Province. [Methods] A population based 1：1 matched case-control study was conducted in Ganyu County, one of the low cancer incidence areas in Jiangsu. Conditional Logistic regression method was used to identify associated risk and protective factors. [Resultsl For esophageal and stomach cancer, the common risk factors were the habits of speed meal （OR esophageal=l.95,OR stomach=l.46）, hot food more （OR esophageal=2.72,OR stomach=2.21） and the cancer family history （OResophageal= 2.02,OR stomach=2.29）. As lung cancer, the earlier （OR=3.63）, longer-term（OR=4.13） and heavier （OR=2.79） smoking, the higher cancer occurence. Tea was the common protective factor for esophageal （OR=0.73）, stomach（OR=0.37）, lung（OR=0.60） and liver （OR=0.27）cancers, garlic was protective factor for preventing esophageal （OR=0.68） and stomach （OR=0.64） cancer. [ Conclusion ] The risk fac- tors for cancer attributed to this study may provide a guide for cancer prevention in Jiangsu Province.
出处
《中国肿瘤》
CAS
2008年第1期5-7,共3页
China Cancer
基金
江苏省医学135工程重点人才研究基金(RC200390)
