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肝X受体在代谢和炎症中的作用 被引量:3

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出处 《临床心血管病杂志》 CAS CSCD 北大核心 2007年第11期806-810,共5页 Journal of Clinical Cardiology
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  • 1WILLYPJ,UMESONOK,ONGES,etal.LXR,a nuclear receptor that defines a distinct retinoid response pathway[J].Genes Dev,1995,9:1033-1045.
  • 2LEHMANN J M,KLIEWER S A,MOORE L B,et al.Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway[J].J Biol Chem,1997,272:3137-3140.
  • 3GLASS C K,OGAWA S.Combinatorial roles of nuclear receptors in inflammation and immunity[J].Nat Rev Immunol,2006,6:44-55.
  • 4COLLINS J L,FIVUSH A M,WATSON M A,et al.Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines[J].J Med Chem,2002,45:1963-1966.
  • 5MITRO N,MAK P A,VARGAS L,et al.The nuclear receptor LXR is a glucose sensor[J].Nature,2007,445:219-223.
  • 6PEET DJ,TURLEY S D,MA W,et al.Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha[J].Cell,1998,93:693-704.
  • 7CHIANG J Y,KIMMEL R,STROUP D.Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1)transcription by the liver orphan receptor (LXRalpha)[J].Gene,2001,262:257-265.
  • 8SCHWARTZ K,LAWN R M,WADE D P.ABC1 gene expression and apoA-I-mediated cholesterol efflux are regulated by LXR[J].Biochem Biophys Res Commun,2000,274:794-802.
  • 9OUT R,HOEKSTRA M,MEURS I,et al.Total body ABCG1 expression protects against early atherosclerotic lesion development in mice[J].Arterioscler Thromb Vasc Biol,2007,27:594-599.
  • 10BERGE K E,VON BERGMANN K,LUTJOHANN D,et al.Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8[J].J Lipid Res,2002,43:486-494.

同被引文献67

  • 1钱宗杰,曾秋棠.冠心病患者巨噬细胞肝X受体的活化与胆固醇外流[J].中国病理生理杂志,2006,22(11):2146-2150. 被引量:2
  • 2Hong C et al. Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr Opin Genet Dev, 2008, 18(5): 461-467.
  • 3Dai X et al. Effect of T0901317 on hepatic proinflammatory gene expression in apoE- mice fed a high-fat/high-cholesterol diet. Inflammation, 2007, 30(3-4): 105-117.
  • 4Zelcer Net al. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest, 2006, 116(3): 607- 614.
  • 5Joseph SB et al. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med, 2003, 9(2): 213-219.
  • 6Terasaka Net al. Liver X receptor agonists inhibit tissue factor expression in macrophages. FEBS J, 2005, 272(6): 1546- 1556.
  • 7Blaschke F et al. A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor. Circ Res, 2006, 99(12): e88-99.
  • 8Pascual Get al. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPARgamma. Nature, 2005, 437(7059): 759-763.
  • 9Walcher et al. LXR Activation reduces proinflammatory cytokine expression in human CD4-positive lymphocytes. Arterioscler Thromb Vasc Biol, 2006, 26(5): 1022-1028.
  • 10Geyeregger R et al. Liver X receptors regulate dendritic cell phenotype and function through blocked induction of the actin-bundling protein fascin. Blood, 2007, 109(10): 4288- 4295.

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