摘要
采用激光心肌血管重建术的方法对动物实验模型缺血性心脏病的治疗进行探讨。杂交犬３４条分为３组：对照组１０条、激光心肌血管重建术组８条，激光心肌血管重建＋心脏网膜固定术组１６条。分别监测了ＥＫＧ（ＳＴ－Ｔ）、心输出量、放射性同位素８６Ｒｂ摄取分数和组织学检查等。结果显示激光打孔后ＳＴ－Ｔ改变恢复、心输出量增加、心肌血供增加，以激光心肌血管重建术＋心脏网膜固定术组。组织学检查发现激光孔道２周后被纤维组织填塞，但其中有许多新生壁薄腔大的血管及有形成小动脉趋势的血管。激光孔道及新生的血管和形成的网膜－心肌侧支循环，都能为缺血心肌提供血液并改善心功能。
Thirty four mongrel dogs were divided into control group (C-group, n=10), Laser myocardial revascularization (LMR) group (L-group, n=8) and Laser myocardial revasculerization+cardio-ometaplexy group (O=group ,n=16).They were monitored by EKG and NCCOM3 for ST-T and cardial output (CO).Fractional 86 Rb uptake and biopsy were obtained. Our results revealed that the change of ST-T segment recovered instantly and the CO increased after LMR. The channels of LMR remained patent and communicated with ventriculal cavity for 2 weeks, and then closed by clot and fibrosis. But it was interesting to find many newborn vessels and some of them were likely to form artery. The blood flow in the ischemical myocardium may improve by the channels of LMR, the newborn vessels and the lateral circulation between the ischemical region and grafted omentum strip.
出处
《南通医学院学报》
1997年第3期307-308,共2页
ACTA Academiae Medicinae Nantong
关键词
激光心肌再血管化
心脏网膜固定
缺血性心脏病
Laser transmyocardial revascularization Cardio-ometaplexy Ischemic heart desease
