摘要
为探讨Rab23蛋白在各种器官中的功能情况,研究了Rab23蛋白在小鼠不同器官组织中的表达。选用性成熟的正常成年雌、雄小鼠的各种不同器官的组织,利用免疫组织化学方法,系统地检测Rab23蛋白的表达。结果显示Rab23蛋白在小鼠的脑、卵巢、精巢、乳腺和胃组织中有明显的表达,而在心脏、肝脏、肠、肺、胸腺、肾脏和脾脏中没有表达。Rab23蛋白在小鼠脑、性腺、乳腺和胃中的特异性表达,表明该分子在这些器官组织正常功能的维持中可能具有一定的作用。实验结果还为深入研究Rab23蛋白的分子功能提供了新资料。
In order to explore the function of the Rab23, the expression of the Rab23 protein in various organs of mice was investigated. Fresh tissues were taken from mature adults of male and female miee and the expression of the Rab23 protein was detected by using immunohistochemistry analysis. Rab23 protein expression was detected in tissues of the brain, ovaries, testis, mammary glands and stomach in miee. But no detectable expression was found in tissues of the heart, liver, intestines, lungs, thymus, kidneys and spleen. The specific tissue locations of the Rab23 protein suggest that Rab23 may play a role in keeping the normal funetions in these organs and tissues. The results give new data for understanding the molecular function of Rab23.
出处
《山东大学学报（理学版）》
CAS
CSCD
北大核心
2008年第1期1-3,7,共4页
Journal of Shandong University(Natural Science)
基金
国家自然科学基金资助项目(30671072)
