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生育年龄月经失调骨密度状况研究 被引量:6

STUDY OF THE BONE MINERAL DENSITY IN REPRODUCTIVE PERIOD WITH IRREGULAR MENSTRUATION
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摘要 目的了解月经失调对生育年龄女性骨密度的影响。方法选择2005年5月~2006年6月来妇科门诊首次就诊,以月经周期不规律为主诉的20~39岁生育年龄患者共134例。用双能X线骨密度仪分别测量其2~4腰椎及双侧股骨颈的骨密度。结果134例患者中有28例患者2~4腰椎或双侧股骨颈的骨密度低于正常范围,其中达到骨量减少标准(T值-1^-2.5)的有16例,达到骨质疏松标准(T值<-2.5)的有12例。线性相关分析发现28例患者体质量、体质量指数、月经不调年限与腰椎T值、股骨颈T值、2~4腰椎骨密度、左侧股骨颈骨密度、右侧股骨颈骨密度均有密切相关性。χ2检验分析发现,有母系骨质疏松家族史患者骨密度低于正常值的发生率明显高于无母系骨质疏松家族史的患者(P<0.01)。结论月经不调对生育年龄女性骨密度有影响,发病时间越长影响越大,尤其是低体质量、有母系骨质疏松家族史的高危患者。 Objective To study the effect of irregular menstruation on bone mineral density (BMD) of women in reproductive period. Methods From May 2005 to June 2006,measured BMD of both lumbar spines and hips by dual energy X-ray absorptionetry (DEXA) in 134 patients (aged 20439) with irregular menses. Results Of the 134 patients, there were 28 cases whose BMD was decreased. Among them 16 patients appeared as less BMD whose T value was from -1 to-2.5,and 12 patients appeared as osteoporosis whose T value was less than -2.5. Linear correction analysis showed that there were positive correlation between BMD and the factors of weight,body mass index,time of irregular menstruation. The ratio of decreased BMD in mother kindred osteoporosis was significiantly higher than that in non mother kindred osteoporosis( P〈0.01). Conclusion Irregular menstruation has influence on BMD for the women in reproductive period,especially for whom with low weight and mother kindred osteoporosis.
出处 《河北医科大学学报》 CAS 2008年第1期47-49,共3页 Journal of Hebei Medical University
关键词 月经失调 骨密度 X线 menstruation disturbances bone density X-rays
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