摘要
为了研究我国重要蜱媒病的复合感染情况，本文选择黑龙江林区蜱媒疾病高发区域，以莱姆病、森林脑炎、人巴贝西原虫病、埃立克体等蜱媒病原为目标，应用聚合酶链式反应对该地区采集的全沟硬蜱可能感染的蜱媒病原情况进行检测，以探讨这些蜱媒疾病在媒介全沟硬蜱体内的复合感染状况。结果表明，该地区的全沟硬蜱感染有莱姆病、森林脑炎、人巴贝西原虫病、埃立克体、斑点热等5种疾病的病原体，感染阳性率在1.05％～10.5％之间；在这些感染个体中，将近40％的个体属于复合感染，复合感染的类型有双重感染和三重感染。其中，莱姆病螺旋体和其他病原体复合感染的比例很高；没有发现埃立克体和人巴贝西原虫的复合感染现象。我国蜱媒病原的复合感染情况，理应引起预防、临床和公共卫生相关人员的充分关注。
Total 854 hungry adult taiga ticks Ixodes persulcatus collected from forests from Heilongjiang province were screened for dangerous tick borne pathogens using PCR techniques. These pathogens included 2 Lyme diseases agents, 2 Ehrlichiosis agents, 2 Babesiosis agents and tick borne encephalitis and spotted fever group rickettsia. Prevalence of I. persulcatus ranged from 1.5 % to 10.5% with different pathogens respectively. About 40% ticks were multiply infected with these pathogens. Lyme disease agent Borrelia garinii and B. afzelii appeared to be readily to infect in I. persulcatus combined with other pathogens. Besides the combination types between Ehrlichia spp. and Babesia microti, other types of multiple infections were also detectable. Although no quadruple infection were found coinfected, triple infection were common and might be a cue to know the capacity of ticks to carry multiple pathogens. The knowledge of co-infection would be helpful for practitioners in diagnosis and proper treatment of tick borne diseases.
出处
《寄生虫与医学昆虫学报》
CAS
2007年第4期231-240,共10页
Acta Parasitologica et Medica Entomologica Sinica
基金
国家自然科学基金项目(30400364)
军事医学科学院创新项目基金(0208077)
关键词
复合感染
蜱媒病原
全沟硬蜱
Multiple infection
Tick borne pathogens
Ixodes persulcatus
