摘要
目的总结和分析乳腺导管原位癌伴微小浸润(T_1 mic)的临床和组织病理特征,探讨合理的治疗方法。方法总结自1996年1月至2006年6月底共31名患者32例乳腺导管原位癌伴微小浸润的临床特征,组织病理特征,治疗方法及随访资料。结果经病理诊断的32例乳腺导管原位癌伴微小浸润患者中,最大浸润灶均≤1 mm,其中有27例(84%)临床上可触及肿块,有30例(93.8%)钼靶上有异常表现,病理可见粉刺样结构的病例为19例(59.4%),可见坏死的为20例(62.5%)。25例行腋窝淋巴结清扫术的患者没有一例有腋窝淋巴结转移。经过中位时间为28个月的随访无一例发生复发和转移。结论乳腺导管原位癌伴微小浸润是一个少见的乳腺癌亚型,其预后很好。治疗上应该根据其原位癌成分的病理特点及临床特征进行治疗。
Objective To analyze the clinical and pathological features of breast cancer in situ with microinvasion （T1 mic） and to seek for rationale managements. Methods Thirty-two breast cancer foci in 31 patients from January 1996 to June 2006 were diagnosed as T1 mic. We made an analysis on the clinical and pathological features, treatments and prognosis. Results The 32 T1 mic breast cancer tissues were all with invasive foci ≤ 1 mm. Among them, 27 cases （ 84% ） had palpable masses, 30 （ 93.75% ） presented mammographically-detected lesions, 19 （ 59.4% ） had comedo patterns and 20 （ 62.5% ） demonstrated necrosis. No lymph node metastasis was found in the 25 patients with axillary lymph node dissection. No patients had local recurrence and distant metastasis after a median follow-up of 38 months. Conclusion T1 mic is a less common type of breast carcinoma with extremely good prognosis. We should treat it according to its pathologic features of the accompanying carcinoma in situ and its clinical profiles.
出处
《中华普通外科杂志》
CSCD
北大核心
2007年第12期909-911,共3页
Chinese Journal of General Surgery
关键词
乳腺肿瘤
癌
原位
微小浸润
Breast neoplasms
Carcinoma in situ
Microinvasion
