5Karkkainen MJ,Haiko P,Sainio K,et al.Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins[J].Nat Immunol,2004,5(1):74 - 80
6Baldwin ME,Halford MM,Roufail S,et al.Vascular endothelial growth factor D is dipensable for development of the lymphatic system[J].Mol Cell Biol,2005,25(16):2441 - 2449
7Karkkainen MJ,Ferrell RE,Lawrence EC,et al.Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema[J].Nat Genet,2000,25(1):153 - 159
8Yuan L,Moyoo D,Pardanaud L,et al.Abnormal lymphatic vessel development in neuropilin 2 mutant mice[J].Development,2002,129(19):4797-4806
1Masuda N, Tamaki Y, Sakita I et al . Clinical significance of micrometastases inaxillary lymph nodes assessed by reverse transcription- polymerase chain reaction in breastcancer patients. Clin Cancer Res,2000,6:4 176-4 185
2Jussila, Lotta K. Alitalo. Vascular Growth Factors and Lymphangiogenesis. Physiol Rev,2002,82:673- 700
3Pepper MS.Lymphangiogenesis and tumour metastasis: myth or reality. Clin Cancer Res,2001,7:462 - 468
4Swartz MA. The physiology of the lymphatic system. JADDR, 2001, 50:3-20
5Alitalo K, Carmeliet P. Molecular mechanisms of lymphangiogenesis in health anddisease. Cancer Cell, 2002, 1: 219- 227
6Mandriota SJ, Jussila L, Jeltsch M et al . Vascular endothelial growth factor C mediatedlymphangiogenesis promotes tumour metastasis. J EMBO,2001,20:672 - 682
7Karpanen M, Egeblad MJ, Karkkainen et al . Vascular endothelial growth factor Cpromotes tumour lymphangiogenesis and intralymphatic tumour growth . Cancer Res,2001, 61:1786- 1790
8Banerji S, Ni J, Wang SX et al. LYVE- 1, a new homologue of the CD44 glycoprotein is a lymph- specific receptor for hyaluronan. J Cell Biol,1999, 144:789-801
9Prevo R, Banerji S. Mouse LYVE- 1 is an endocytic receptor for hyaluronan in lymphatic endothelium. J Biol Chem,2001, 276:19 420- 19 430
10Jackson DG, Prevo R, Clasper S et al. LYVE1, the lymphatic system and tumour lymphangiogenesis. Trends Immunol, 2001,22:317 - 321
1Furudoi A,Tanaka S,Haruma K,et al.Clinical significance of vascular endothelial growth factor-C expression and angiogenesisat the deepest invasive site of advanced colorectal carcinoma[J].Oncology,2002,62(2):157-166.
2Franchi A,Massi D,Santucci M,et al.Inducible nitric oxidesynthase activity correlates with lymphangiogenesis and vascularendothelial growth factor-C expression in head and necksquamous cell carcinoma[J].J Pathol,2006,208(3):439-445.
3Ohhashi T,Mizuno R,Ikomi F,et al.Current topics of physiology and pharmacology in the lymphatic system[J].Pharmacol Ther,2005,105(2):165-188.
5Finan M A,DeCesare S,Fiorica J V,et al.Radical hysterectoryfor stage 1B1 vs 1B2carcinoma of the cervix:does the newstaging system predict morbidity and survival[J].GynecolOncol,1996,62(2):139-147.
6He Y,Karpanen T,Alitalo K,et al.Role of lymphangiogenicfactors in tumor metastasis[J].Biochim Biophys Acta,2004,1654(1):3-12.
9Otrock ZK,Makarem JA,Shamseddine AI. Vascular endothe-lial growth factor family of ligands and receptors[J].Blood Cells Molecules and Diseases,2007,(03):258-268.
10Baluk P,Tammela T,Ator E. Path-ogenesis of persistent lymphatic vessel hyperpla-sia in chronic airway inflammation[J].Journal of Clinical Investigation,2005,(02):247-257.