摘要
目的探讨福辛普利联合美托洛尔治疗慢性心力衰竭(CHF)的临床疗效。方法64例CHF患者随机分为治疗组和对照组。对照组应用常规药物(利尿剂、扩血管药物、洋地黄等)治疗,治疗组在应用常规药物治疗基础上加用福辛普利和美托洛尔,服用48周,观察2组临床疗效、心电图改变及超声心动图心功能指标。结果治疗组临床疗效和心电图改善明显优于对照组(P<0.05);与对照组比较,治疗组左室舒张末期内径缩小(P<0.05),左心室射血分数增高(P<0.05)。结论福辛普利联合美托洛尔治疗CHF临床疗效明显。
Objective To investigate the curative effect of fosinopril and metoprolol for the treatment of chronic heart failure（CHF）. Methods Sixty-four patients with CHF patients were randomly divided into the treatment group and the control group. The patients in control group were treated with conventional drugs （ diuretics, vasodilator drug, digitalis）, while the patients in treatment group were treated with fosinopril and metoprolol for 48 weeks on the basis of conventional medication. Clinical effect,electrocardiographic changes and echocardiography heart function indexes were observed. Results The clinical effect and electrocardiographic changes were better in treatment group than these in control group （ P 〈 0.05 ）. Compared with control group, the left ventricular end-systolic dimension was shorter（ P 〈 0.05 ）, left ventricular ejection fraction was higher in treatment group（ P 〈 0.05 ）. Conclusion The curative effect of fosinopril and metoprolol in treatment of CHF is obvious.
出处
《新乡医学院学报》
CAS
2008年第1期47-49,共3页
Journal of Xinxiang Medical University
