摘要
目的观察美托洛尔治疗充血性心力衰竭后,患者血浆脑钠肽（BNP）水平的改变。方法选择心功能Ⅲ～Ⅳ级心衰患者62例,在常规抗心衰基础上加用美托洛尔,观察治疗前后血浆脑钠肽水平的变化。结果心率明显减慢,血压较治疗前降低,左室舒张末期内径（LVDd）缩短,而左室射血分数（LVEF）则较治疗前升高,应用美托洛尔后BNP值明显降低。结论美托洛尔治疗充血性心力衰竭（CHF）的总有效率达80%以上,且BNP明显下降。提示动态监测患者血浆BNP水平可以帮助了解治疗效果及判断预后。
Objective To observe plasma brain natriuretic peptide level by using Metoprolol for congestive heart failure.Methods We chose 62 heart failure patients with Ⅲ-Ⅳ New York Heart Association（NYHA）functional classification,and used Metoprolol on the basis of traditional treatment,then observed the changement of plasma brain natriuretic peptide level during treatment.Results After treatment,patients＇ heart rate,blood pressure and LVDd descended,but LVEF increased.The value of BNP declined obviously,after using Metoprolol.Conclusion We treated congestive heart failure with Metoprolol.The availability ratio was more than 80%,and the value of BNP declined obviously. It implied dynamic monitoring plasma brain natriuretic peptide was helpful in understanding treatment effect and prognosis.
出处
《社区医学杂志》
2008年第1期10-11,共2页
Journal Of Community Medicine
关键词
脑钠肽
美托洛尔
充血性心力衰竭
Brain natriuretic peptide（BNP）
Metoprolol
Congestive heart failure
