摘要
为探索治疗多发性肌炎的有效方法,我们制作了豚鼠实验性自身免疫性肌炎(EAM)模型,用强的松、雷公藤多甙、消炎痛和黄芪分组对照治疗,通过对动物的症状观察、肌电图、肌酶谱、肌肉病理检查结果分析,认为雷公藤多甙与强的松对EAM有相近的良好疗效,黄芪次之,消炎痛无效。
We established experimental autoallergical myositis(EAM)in guinea pig by repeated injection of rabbit muscle hemogenate emusified in Freud ,s adjuvant.The present work is to estimate the effect of prednisone,tripterygium wilfordii (GTW),astragalus membranaceus Bge and indomethacin of EAM through analysis of the change of clinical manifestation,electromyography (EMG),muscle enzymes and pathology,The effecacy of treatment of GTW is similar to prednisone,and better than that of astragalus membranaceus Bge.EAM does not respond to indomethacin.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
1997年第3期147-148,共2页
Journal of Apoplexy and Nervous Diseases
关键词
自身免疫性肌炎
EAM
药物疗法
肌炎
Experimental Auto allergical myositis (EAM) Medical treatment