摘要
目的探讨腰椎间盘突出症伴单侧神经根型疼痛患者，采用骶裂孔复合椎旁胶原酶介入治疗的临床效果。方法对120例伴单侧神经根型疼痛的腰椎间盘突出症患者分别采用单纯骶裂孔介入技术（60例，骶裂孔组）与椎旁介入技术相结合（60例，椎旁＋骶裂孔组）治疗，并对两组进行对照观察。结果两组治疗前后视觉模拟评分（VAS）分别为（7．45±1．25）分及（1．89±1．73）分、（7．34±1．42）分及（3．17±2．00）分。两组治疗前后VAS之差分别为（5．56±2．01）分及（4．30±2．07）分，差异有统计学意义（P〈0．01）。两组治疗后2年Maenab疗效评估有效率分别为95．00％及91．67％。差异无统计学意义；优良率分别为85．00％及66．67％，差异有统计学意义（P〈0．05）。结论骶裂孔复合椎旁胶原酶介入治疗将胶原酶分别注射到脱出的髓核内外两侧，较单纯骶裂孔介入治疗单侧神经根型腰椎间盘突出症临床疗效更加显著。
Objective To discuss the effect of lumbar intervertebral disc protrusion with unilateral nerve root pain in patients with sacral hiatus composite paraspinal collagenase interventional therapy. Method One hundred and twenty patients with lumbar intervertebral disc herniation with unilateral nerve root pain were divided into two groups, group A adopted simple sacral hiatus intervention technique, group B adopted paraspinal intervention technique based on group A. Results The VAS score before and after treatment was （7.45 ± 1.25 ） scores and （1.89 ± 1.73） scores, （7.34 ± 1.42） scores and （3.17 ± 2.00） scores in two groups respectively,the difference of VAS scores before and after treatment was （5.56 ± 2.01 ）scores and （4.30 ± 2.07）scores in two groups respectively, there was significant difference（P〈 0.01 ）. Two years after treatment, the Macnab efficiency rate was 95.00% and 91.67% in two groups respectively, there was no difference, the excellent and good rate was 85.00% and 66.67% in two groups respectively, there was significant difference （P 〈 0.05）. Conclusion Sacral hiatus injection of collagenase on the basis of composite paraspinal injection of collagenase to emerge on both sides of the nucleus pulposus outside is more significant than simply sacral hiatus interventional treatment of nerve root unilateral lumbar intervertebral disc herniation.
出处
《中国医师进修杂志（外科版）》
2008年第1期23-25,共3页
Chinese Journal of Postgraduates of Medicine
基金
天津医科大学第二医院自选课题资助项目（y200606）
关键词
骶裂孔
胶原酶类
椎间盘移位
腰
Sacral hiatus
Collagenases
Interverteberal disk displacement,Lumbar
