摘要
多囊卵巢综合征（PCOS）是一种好发于青春期和生育期的内分泌疾病，以雄激素过多和持续不排卵为主要特征，有35％-60％的患者合并有中心性肥胖。近年来很多研究表明，PCOS与心血管疾病有着密切联系，尤其是肥胖患者。肥胖通过加重胰岛素抵抗、血脂异常、高血压、血管功能的改变及低度慢性炎症等多方面因素促进心血管疾病的进展。现就肥胖型PCOS与心血管疾病的联系，肥胖加重心血管疾病的机制和治疗进行综述。
Polycystic ovary syndrome （PCOS）is an endocrine disease, occurring in adolescent and child-beating period, PCOS is primarily charactefistized by hyperandrogenism and ctu＇onic anovulation, central obesity is present in 35 % - 60 % women with PCOS. Recently, many studies have manifested there is significant association between PCOS and cardiovascular diseases, especially in obese women with PCOS. In PCOS patients, obesity can promote the developping of cardiovascular disease by aggravating many aspects such as insulin resistance, hyperlipemia, hypertension, vascular function, low-grade chronic inflammation and so on This article reviews relationship between obesity-type PCOS and cardiovascular diseases, mechanism of obesity aggravating cardiovascular diseases and therapy.
出处
《医学综述》
2008年第2期287-289,共3页
Medical Recapitulate
关键词
多囊卵巢综合征
心血管疾病
肥胖
Polycystic ovary syndrome
Cardiovascular disease
Obesity
