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毛细管区带电泳对M蛋白的免疫分型 被引量:5

Immunological classification of M protein with capillary zone electrophoresis
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摘要 目的探讨毛细管区带电泳-免疫削减法(IS-CZE)在M蛋白免疫分型中的应用价值。方法运用血清免疫固定电泳(IFE)对645例患者血清进行免疫分型,将其阳性结果与IS-CZE法免疫分型结果进行比较。结果IS-CZE法出现M蛋白的阳性率为20.3%,IFE为22.6%,分型结果基本一致。结论对于特征性的、大量的单克隆免疫球蛋白,毛细管区带电泳可有效完成对M蛋白的免疫分型。 Objective To investigate the applicable significance of IS-CZE in immunological classiffication of M protein. Methods Immunological classifying of the serum of 645 patients was performed with immunofixation electrophoresis (IFE) and the results were compared with those of immunosubtraction-capillary zone electrophoresis(IS- CZE). Results The positive rate of M protein by the method of IS-CZE was 20.30//00, and that of IFE was 22.60//00. The results of classification of both methods matched well. Conclusion Capillary zone electrophoresis can be applied in classifying typical M protein successfully.
出处 《检验医学与临床》 CAS 2008年第2期72-73,75,共3页 Laboratory Medicine and Clinic
关键词 毛细管电泳 免疫电泳 血蛋白质类 capillary zone electrophoresis immunoelectrophoresis blood proteins
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