摘要
目的探讨并总结急播散性脑脊髓炎的临床表现特征、治疗策略及转归情况。方法通过收集华中科技大学附属同济医院神经内科住院治疗的急性播散性脑脊髓炎病例,详细分析患者发病的临床表现及相关辅助检查结果,并对其治疗后的转归情况进行随访调查。结果4例患者中3例为中年,1例为青壮年,均急性起病,脑和脊髓损害的表现在时间上重叠出现,有明显的脑脊液及影像学检查改变,在急性期采用甲基强的松龙冲击治疗,结合神经营养及支持治疗均好转。结论急性播散性脑脊髓膜炎临床表现多种多样,在神经内科临床工作中较易误诊及漏诊,如能早期诊断并早期应用激素治疗效果良好,可极大改善其预后。
Objective To observe the clinical characteristics,treatment strategy and prognosis of acute dis- seminated encephalomyelitis （ADEM）. Methods The patients with ADEM in Tongji Hospital Affiliated to Huazhong Science and Technology University and their clinical signs and symptoms were analyzed. The results of all clinical tests were recorded in detail and analyzed systematically. The follow-up work was done to obtain the ef- fect of treatment and prognosis. Results We collected four patients were collected. Three of them were in their middle age and one was in his prime of life. They all got the acute attack of ADEM and presented the symptoms of both brain and spine at tbe same period,with the abnormalily of cerebral spinal fluid and CT/MRI scan. The four patients were treated with methylprednisolone and other neurotrophic and support therapy. All the patients showed good efficacy after therapy. Conclusions The clinical presentation of ADEM is very complicated,so it is very likely to be ignored and mistaken in the clinical work. The diagnosis should be determined as early as possible and most of the patients will respond to the treatment of high dose methylprednisolone. The prognosis is good if the treatment is in time.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2007年第6期668-670,共3页
Journal of Apoplexy and Nervous Diseases
关键词
急性播散性脑脊髓炎
临床特征
治疗
转归
Acute disseminated encephalomyeliti
Clinical characteristic
Treatment
Prognosis
