期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

XPC基因多态性与卵巢癌发病风险的关联研究

Correlation of polymorphisms in xeroderma pigmentosum group C to the risk of ovarian carcinoma
原文传递
导出
摘要 研究表明，存在于DNA修复基因的单核苷酸多态性（SNP）可能与个体的DNA修复能力有关，且可能导致不同个体疾病遗传易感性的差异。XPC（xeroderma pigmentosum group C）基因是核苷酸切除修复系统的重要成员，定位于染色体3p25，其第8外显子C／T、第9内含子PAT-／＋及第15外显子A/C多态可能与肺、
作者 周荣秒 王娜 郭炜 张晓娟 董秀娟 李琰
机构地区 河北医科大学第四医院河北省肿瘤研究所分子生物学研究室
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2008年第1期91-92,共2页 Chinese Journal of Epidemiology
关键词 卵巢肿瘤 基因多态性 遗传易感性 Ovarian cardnoma Polymorphism Susceptibility
分类号 R737.31 [医药卫生—肿瘤]
  • 相关文献

参考文献5

  • 1胡志斌,王永岗,马红霞,谭文,钮菊英,林东昕,沈洪兵.DNA修复基因XPCAla499Val、Lys939Gln多态与肺癌易感性[J].中华医学遗传学杂志,2005,22(4):415-418. 被引量：15
  • 2Shen H, Sturgis EM, Khan SG, et al. An intronic poly (AT) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck. Cancer Res, 2001,61 ( 8 ) : 3321-3332.
  • 3Miller SA,Dykes DD,Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acid Res, 1988,16(3):1215.
  • 4王永岗,邢德印,谭文,汪良骏,唐平章,林东昕.DNA修复基因XPC PAT遗传多态与肺癌的关系[J].中华肿瘤杂志,2003,25(6):555-557. 被引量：14
  • 5Qiao Y,Spitz MR, Guo Z, et al. Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. Mutat Res, 2002,509(1-2) :165-174.

二级参考文献11

  • 1Wei Q, Cheng L, Hong WK, et al. Reduced DNA repair capacity in lung cancer patients. Cancer Res, 1996, 56∶4103-4107.
  • 2Wei Q, Cheng L, Amos CI, et al. Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study. J Natl Cancer Inst, 2000, 92∶1764-1772.
  • 3Sugasawa K, Ng JM, Masutani C, et al. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol Cell, 1998, 2∶223-232.
  • 4Khan SG, Metter EJ, Tarone RE, et al. A new xeroderma pigmentosum group C poly(AT) insertion/deletion polymorphism. Carcinogenesis, 2000, 21∶1821-1825.
  • 5Vodicka P, Kumar R, Stetina R, et al. Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single strand breaks in DNA. Carcinogenesis, 2004,25∶757-763.
  • 6Sanyal S, Festa F, Sakano S, et al. Polymorphisms in DNA repair and metabolic genes in bladder cancer. Carcinogenesis, 2004,25∶729-734.
  • 7Ke X, Collins A, Ye S. PIRA PCR designer for restriction analysis of single nucleotide polymorphisms. Bioinformatics, 2001, 17:838-839.
  • 8Don RH, Cox PT, Wainwright BJ, et al. 'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res, 1991, 19∶4008.
  • 9Volker M, Mone MJ, Karmakar P, et al. Sequential assembly of the nucleotide excision repair factors in vivo. Mol Cell, 2001, 8∶213-224.
  • 10Janicijevic A, Sugasawa K, Shimizu Y, et al. DNA bending by the human damage recognition complex XPC-HR23B. DNA Repair (Amst), 2003, 2∶325-336.

共引文献21

中华流行病学杂志
2008年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部