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非心脏手术围术期与心肌梗死急性期心肌酶谱和肌钙蛋白Ⅰ比较

Comparison of Cardiac Enzymes and cTnI in Noncardiac Perioperative period and AMI period
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摘要 目的:初步探讨围术期心肌缺血性疾病的诊断标准。方法:选择30例非心脏手术的老年患者(A组),测定其术前、术中、术毕和术后第1、2天的心肌酶谱和肌钙蛋白Ⅰ(cTnI)的值。30例经冠脉造影术(CAG)证实无冠脉病变的老年患者(B组),记录其PCI术前的心肌酶谱和cTnI的值。30例心内科急性心梗(AMI)老年患者(C组),测定其起病当天,起病后第1、2天的心肌酶谱和cTnI的值。结果:非心脏手术围术期除术前外,其余时间点的心肌酶谱与B组比较,均有显著差异(P<0.05);与C组比较,除CK外心肌酶谱各指标均未达到C组的标准。而非心脏手术围术期的cTnI与B组比较无显著差异(P>0.05),但与C组比较差异显著(P<0.05)。结论:cTnI是围术期心肌缺血性疾病的特异性指标。 Objective:To preliminarily study the diagnosis standard of noncardiac perioperative ischemic diseases. Methods:The values of cardiac enzymes and cTnI of thirty older patients (age≥60 years) for noncardiac operations under general anaesthesia who were determined on the day before operation, intraoperative period, postoperative 0, 24, 48 h(Group A) were recorded, and the values of those before coronary angiography(CAG) of thirty older patients scheduled for no main coronary artery diseases demonstrated by PCI (Group B)and those of thirty older patients scheduled for acute my cardial in farction(AMI) on first, second, third day of AMI(Group C) also were recorded. Results: Every cardiac enzyme during noncardiac perioperations changed obviously, compared with Group B (P〈0.05), while all the cardiac enzymes except CK did not reach the level of Group C. cTnI of Group A had no difference with that of Group B (P〉0.05), but had remarkable difference with that of Group C (P〈0.05). Conclusion: cTnI is an specific marker in diagnosis of peroperartive ischemic diseases.
出处 《中国临床医学》 北大核心 2007年第6期764-766,共3页 Chinese Journal of Clinical Medicine
关键词 非心脏手术 围术期 心肌酶谱 肌钙蛋白I Noncardiac operations Perioperations Cardiac enzymes Cardiac troponin I
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参考文献3

  • 1Mangano DT, Browner WS, Hollenberg M, et al. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery[J]. N Engl J Med, 1990, 323 : 1781-1788.
  • 2Alyanakian MA,Dehoux M,Chatel D,et al. Cardiac troponin Ⅰ in diagnostic of perioperative myocardial infarction after cardiac surgery[J]. Cardiothnrac Vasc Anest h, 1998,12 (3) : 288-294.
  • 3Mair J,Larue C.Mair P,et al. Use of cardiac troponin Ⅰ to diagnose perioperative myocardial infarction in CABG[J]. Clin Chem, 1994.40( 11Pt 1 ) :2066- 2070.

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