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肝硬化:门脉分流指数与Child-Pugh分类

Hepatic cirrhosis: portal shunt indexes and Child-Pugh classification
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摘要 目的:探讨门脉分流指数与Child-Pugh分类的相关性,以了解其对肝硬化的诊断效能.方法:用 ̄(99m)Tc04-直肠给药法进行门静脉循环y照相,计算门脉分流指数(SI).并与胃镜、胃肠钡气双重造影和CT进行比较。结果:SI值正常人为7.1%±2.3%,慢性肝炎12%±3.5%,肝硬化Child-PushA分类为24.5%±12.5%,B分类为48.3%±21.0%,C分类为83.6%±3.9%。若以慢性肝炎均值+2s即19%作判别阈,肝硬化患者总阳性率为90.0%。优于上述其他方法。特异性为100%。准确率为94.7%。单纯Child-PughA分类,敏感性80%,特异性100%,准确率94.5%。结论:门脉分流指数的测定有可能早期诊断肝硬化,适合临床推广应用。 Objectives: Correlation of portal shunt indexes (SI) with Child-Pugh was made. Their diagnostic efficacy in hepatic cirrhosis was evaluated. Methods: SI were determined through portal circulation imaging by per-rectal 99m Tc 04.Comparison was also made with gastroscopy, double contrast GI series and CT. Results: The SI for normal controls was 7.1 %±2.3%; chronic hepatitis, 12%±3.5%;cirrhosis, Child-Pugh A 24.5%±12.5%,B48.5%±21.0% and C 83.6%±39.%. If the threshold for cirrhosis was set at the mean +2s of chronic hepatitis, namely 19%, the sensitivity was 90.0%, superior to the above other methods, The specificity was 100%, and accuracy 94.7%. If only Child-Pugh A was dealt with, the sensitivity was 80%, specficity 100% and accuracy 94.5%. Conclusions:SI determination is capable in diagnosing cirrhosis at its early stage,
出处 《中华消化杂志》 CAS CSCD 北大核心 1997年第4期216-217,共2页 Chinese Journal of Digestion
关键词 肝硬化 门脉循环 门脉分流指数 Hepatic cirrosis Portal circulation imaging Portal shunt index
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  • 1迟宝荣,中华核医学杂志,1996年,16卷,52页

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