摘要
目的观察生理盐水对人工肝血浆置换治疗重型肝炎中低血压的预防作用。方法109例重型肝炎患者进行血浆置换治疗共260例次,观察血浆置换前10min始静脉滴注生理盐水或血浆200ml组,与对照组(不补液)在血浆置换治疗中发生低血压的情况。结果260例次血浆置换治疗有12例次(4.62%),其中对照组9例次(10%)、生理盐水200ml组2例次(2.27%)、血浆200ml组1例次(1.22%)发生了低血压,均出现于血浆置换开始5～30min内。与对照组比较,生理盐水200ml组(χ2=4.582,P<0.05)、血浆200ml组(χ2=4.544,P<0.05)低血压发生率明显降低,有统计学差异。结论重型肝炎患者血浆置换前静脉滴注生理盐水或血浆200ml,能有效预防低血压的发生。
Objective To evaluate the causation and prevention of hypotension happening in severe hepatitis patients undergoing artificial liver system about plasma exchange. Methods A total of 109 cases with severe hepatitis were treated by observation groups were beginning plasma exchange for 260 times. Patients of the to be given 200ml physiological saline or plasma from 10 minutes before treatment, as patients of the control group were given nothing. To observe on the hypotension occurrence for these patients during their treatments. Results Blood pressure reduced in 5-30 minutes after plasma exchange for 12 times （4.62%） in 260 times. It happened 9 times （10%） in the control group, 2 times （2.27%） in the group 200ml physiological saline, 1 time （1.22%） in the group 200ml plasma. Compared with the control group, there was a significant decline in the group 200ml physiological saline（x^2=4.582,P〈0.05） and the group 200ml plasma（x^2= 4.544,P 〈0.05） in terms of the incidence of hypotension. Conclusion The incidence of hypotension in severe hepatitis patients, who were given 200ml physiological saline or plasma before plasma exchange, can effectively reduce.
出处
《药品评价》
CAS
2007年第6期419-421,共3页
Drug Evaluation
关键词
人工
血浆置换
肝功能衰竭
低血压
预防和控制
Liver, Artificial
Plasma Exchange
Liver Failure
Hypotension
Prevention ＆ control
