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干扰素-γ治疗特发性肺纤维化的研究进展 被引量:2

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作者 叶君 梁标
出处 《临床肺科杂志》 2008年第1期62-63,共2页 Journal of Clinical Pulmonary Medicine
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参考文献11

  • 1钱皓瑜,马希涛.特发性肺纤维化患者的Th1/Th2细胞因子失衡[J].中国误诊学杂志,2004,4(7):1068-1069. 被引量:5
  • 2Eickelberg O, Pansky A, Koehler E, et al. Molecular mechanisms of TGF(betta) antagonism by interferon-γ and cycloporine A in lung fibrosis ,2001,15 (3) :797 - 806.
  • 3陈莹,董静,陈杰.γ-干扰素对矽肺大鼠肺脏白介素-4和转化生长因子-β_1蛋白表达的影响[J].中华劳动卫生职业病杂志,2004,22(5):350-353. 被引量:7
  • 4高晓方,崔社怀.干扰素γ及地塞米松对实验性肺纤维化大鼠血清IL-4、SP-A含量的影响[J].实用医学杂志,2004,20(5):498-500. 被引量:5
  • 5Ziesche R, Hofbauer E, Wittmann K, et al. A preliminary study of long-term treatment with interferon-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N Engl J Med, 1999,341: 1264 - 1269.
  • 6Raghu G, Brown KK, Bradford WZ, et al. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med,2004,350:125 - 133.
  • 7Sanjay kalra MD ,james P, utz MD, et al. Interferon Gamma-1b Therapy for Advanced Idiopathic Pulmonary Fibrosis. Mayo Clin Proc, 2003, 78 : 1082 - 1087.
  • 8Hillman R, Tchamouroff S, Denning DW, et al. A phase Ⅲ study of diseases or familial IPF, may have an increased risk of adverse recombinant human interferon gamma to prevent opportunistic in-outcome when treated with interferon-1b, fections in advanced HIV disease. AIDS Res Hum Retroviruses ,2001,17 :789 - 797.
  • 9Honor I,Nunes H, Groussard O, et al. Acute Respiratory. Failure after Interferon-γTherapy of End-Stage Pulmonary Fibrosis. Am J Respir Crit Care Med,2003 ,167 :953 -957.
  • 10Selman M. A dark side of interferon-γ in the treatment of idiopathic pulmonary fibrosis? Am J Respir Crit Care Med,2003 ,167 :945 -946.

二级参考文献20

  • 1Wallace WA, Ramage EA, Lamb D, et al. A type-2 (Th2-1ike) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis. Clin Exp Immunol, 1995,101(3): 436-441
  • 2Gurujeyalakshmi G, Giri SN. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregtulation of TGF - beta and procollagen Ⅰ and Ⅲ gene expression. Exp Lung Res, 1995, 21(5) :791 - 808
  • 3Lasky JA, Ortiz LA. Antifibrotic therapy for the treatment of pulmonary fibrosis. Am J Med Sci, 2001, 322(4) :213 - 221
  • 4Ando M, Miyazaki E, Fukami T, et al. Interleukin-4-producing cells in idiopathic pulmonary fibrosis: an immunohistochemical study. Respirology, 1999, 4(4):383-391
  • 5Hagimoto N, Kuwano K, Miyazaki H, et al. Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. Am J Respir Cell Mol Bio, 1997, 17(3): 272-278
  • 6Maeyama T,Kuwano K,Kawasaki M,et al.Attenuation of bleomycin-Induced pneumopathy in mice by monoclonal antibody to interleukin-13[J].Am J Physiol,,2001,280(6):1128-1137.
  • 7Hashimoto S,Gon Y,Takeshita I,et al.IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase-dependent pathway[J].J Allergy Clin Immunol,2001,107(6):1001-1008.
  • 8Doucet C, Brouty-Boye D, Pottin-Clemenceau C, et al. Interleukin(IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma[J]. J Clin Invest ,1998,101(10):2129-2139.
  • 9Spinozzi F, Agea E, Russano A, et al.Th2-type cytokines and the Fas way to pulmonary fibrosis:comment on the article by Atamas et al[J]. Arthritis Rheum,2000,43(1):236-238.
  • 10Lukacs NW, Hogaboam C, Chensue SW, et al. Typel/type2 cytokine paradigm and the progression of pulmonary fibrosis. Chest, 2001,120( 1Suppl): 5S-8S.

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