摘要
随着工业的迅速发展,迄今为止,已有大约10万种化学物进入人们的日常生活.人们在生产和生活中接触的许多种环境化学物都会影响人类的生殖功能,使人类的生育能力特别是精子的质量和数量发生显著改变.环境化学物所造成的生殖损伤日益受到人们的重视,检测方法和检测技术日益成熟和完善.但大多数环境化学物对生殖的损害目前尚未得到全面地研究和认识,某些毒物的生殖毒性也需要重新认识与评价,生殖毒理学的研究任务迫切而艰巨.动物实验是生殖毒性评价中最主要的方法.在总结近年来国内外相关研究基础上综述了环境化学物动物实验中雄(男)性生殖损伤评价指标及检测技术,以期对环境化学物生殖毒性评价提供借鉴和参考.
With the rapid development of industry, about 100,000 kinds of chemicals have entered into human being＇s daily life. The exposure to many chemicals will impact on human reproductive functions and cause significant change of procreate ability, especially of the semen＇s quality and quantity. People have paid more attentions to the reproductive damage of environmental chemical pollutants （ECPs）and the technology and methods of reproductive damage assessment are becoming perfect. But the toxic effects of most ECPs have not yet been studied. Animal experiment is the main method of reproductive toxicity assessment. This paper described and discussed the development of the indications of male reproductive toxicology, in order to provide references to the assessment of reproductive toxicity of ECPs.
出处
《生态毒理学报》
CAS
CSCD
2007年第4期381-389,共9页
Asian Journal of Ecotoxicology
基金
国家自然科学基金项目(No.90406024)
国家高技术研究发展规划(863)项目(No.2006AA03Z330)
关键词
环境化学物
雄性生殖毒性
生殖损伤指标
检测技术
environmental chemical pollutants （ECPs）
male reproductive toxicity
indications of reproductive damage
detection techniques
