摘要
目的探讨血清泌乳素(PRL)测定值对女性垂体瘤患者的诊断价值。方法对174例女性行血清泌乳素浓度测定,其中84例为垂体瘤患者。按照诊断试验原则,计算出灵敏度(Se)、特异度(Sp)、阳性预告值(+Pr)、阴性预告值(-Pr)、阳性似然比(+LR)、阴性似然比(-LR)。结果对女性垂体瘤患者其血清泌乳素截断点(分界值)为20ng/ml,灵敏度(Se)为82.6%,特异度(Sp)为87.4%.对血清泌乳素超过20ng/ml的患者,阳性预告值(+Pr)为87.6%。结论排除对泌乳素有影响的其他疾病,当血清泌乳素超过20ng/ml时,其患垂体瘤的阳性诊断价值超过90%。
Objective To explore the diagnostic value of serum prolactin concentrations in females who have pituitary tumor. Methods Studied serum prolactin concentrations in 174 female patients. Eighty-four patients has pituitary tumor.ACcording to diangnostic test, sensitivity, specificity, positive predictive value,negative predictive value, positive likelihood ration, negative likelihood ration were calculated. Results It is concluded that the cut off value of serum prolactin in females who have pituitary tumor is 20ng/ml. Sensitivity is 82.6%. Specificity is 87.4%. When serum prolactin concentration is above 20ng/ ml,positive predictive value is 87.6%. Conclusion If some other diseases to affect prolactin have been ruled out ,when serum prolactin is above 20ng/ml,the positive diagnositie value that the patient has pituitary tumor is above 90%.
出处
《中国现代医药杂志》
2007年第12期36-38,共3页
Modern Medicine Journal of China
关键词
垂体腺瘤
泌乳素
灵敏度
特异度
预告值
Pituitary tumor Prolactin Sensitivity Specificity Predictive value
