摘要
目的：观察益肾泻浊方对大鼠肾小球系膜细胞增殖的影响。方法：采用灌胃法给予健康大鼠及实验性慢性肾功能衰竭大鼠益肾泻浊方冲剂，观察给药后大鼠血清对肾小球系膜细胞增殖的影响。结果：与灌服生理盐水的对照大鼠相比较，前者能明显抑制系膜细胞的增殖（Ｐ＜０．０１）。结论：该方能延缓慢性肾功能衰竭进程。
Objective:To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation. Methods: YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed. Results: The serum could obviously inhibit the MSC proliferation.Compared with control rats to which physiological saline was given, the difference was significant (P<0.01).Conclusion: YSXZR could postpone CRF progress.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1997年第7期423-424,共2页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然基金
关键词
益肾泻浊方
肾功能衰竭
中医药疗法
Yishen Xiezhuo Recipe, glomerular mesangium cell proliferation
