摘要
目的:为医师选择降压药提供参考。方法:比较370例原发性高血压患者应用6类15种单药治疗的降压疗效。结果:除多沙唑嗪外,各单药均有效降压;多沙唑嗪和托拉塞米降舒张压的效果较逊。结论:长效钙拮抗药、血管紧张素转换酶抑制剂、血管紧张素受体拮抗药以及特拉唑嗪、吲达帕胺均能单药有效降压。低剂量多沙唑嗪和托拉塞米不建议单独使用治疗高血压。
OBJECTIVE： To provide references for clinicians in the choice of antihypertensive drugs.METHODS： The antihypertensive efficacy 6 classes（or 15 kinds） of antihypertensive drugs in a monotherapy in the treatment of 370 patients with essential hypertension（EH） were compared.RESULTS： The blood pressure was effectively lowered by all of the antihypertensive drugs except doxazosin, and doxazosin and torasemide showed inferior efficacy in the reduction of diastolic blood pressure （DBP） .CONCLUSION：Calcium antagonists with prolonged action,angiotensin converting enzyme inhibitor（ACEI）,angiotensin receptor antagonist,and the monotherapy of Terazosin or Indapamide can all effectively bring down the blood pressure.It is suggested that low- dose doxazosin and torasernide should not be used alone in treating essential hypertension.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第35期2762-2764,共3页
China Pharmacy
关键词
原发性高血压
降压药
单药治疗
Essential hypertension
Antihypertensive drug
Monotherapy
