摘要
目的:总结POEMS综合征的临床特征,提高对POEMS综合征的诊疗认识。方法:回顾性分析5例PO-EMS综合征的一般资料、临床表现、辅助检查、治疗及预后等。结果:5例患者主要临床表现均有多发性周围神经病变、皮肤损害、水肿、不同程度的肝脾肿大及内分泌病变。治疗以激素及免疫球蛋白为主,预后多不良。结论:POEMS综合征是一种累及多系统的疾病,与浆细胞病关系密切,临床表现复杂多样,目前认识尚有不足,应注意多系统检查提高临床诊疗水平。
Objective： To summarize the clinic characteristics of POEMS syndrome and to improve the recognition of this disease. Methods： The general data, clinical manifestations, auxiliary examinations, treatments and prognosis of five cases of POEMS were analyzed retrospectively. Results： 5 cases all presented with multiple peripheral neuropathy, skin lesion, edema, different degree of splenohepatomegalia and endocrinopathy. These patients were mainly treated by glucocorticosteroid and immunoglobulin and the prognosis was poor. Conclusions： POEMS syndrome involves multisystem of the body. It is closely related to plasma cell dyscrasias. Its clinical manifestation was complicated. The recognition of this disease is deficient and careful examinations of multisystem may be helpful in diagnosis of the disease.
出处
《脑与神经疾病杂志》
2007年第6期440-442,共3页
Journal of Brain and Nervous Diseases
