5Al-Jebawi A F, Lassman M N, Abourizk N N. Lactic acidosis with therapeutic metformin blood level in a low-risk diabetic patient[J]. Diabetes Care, 1998,21 : 1364-1365.
3Vesterqvist D, Nabbie F, Swanson B. Determination of metformin in plasma by high-performance liquid chromatography after ultrafiltration. J Chromatogr B,1998,716(1-2):299-304.
4Zhang M,Moore GA,Lever M,et al.Rapid and simple high-performance liquid chromatographic assay for the determination of metformin in human plasma and breast milk.J Chromatogr B,2001,766(1):175-179.
5Ruggiero-Lopez D,Lecomte M,Moinet G,et al. Reaction of Metformin with Dicarbonyl Compounds Possible Implication in the Inhibition of Advanced Glycation End Product Formation. Biochemical Pharmacology,1999,58(11):1 765-1 773.
6Tache F, David V, Farca A, et al. HPC-DAD deternin-ation of metformin in human plasma using derivatization with p-nitrobenzoyl choride in a biphasic system. Microchemical Journal,2001,68(1):13-19.
7Zarghi A,Foroutan SM,Shafaati A,et al.A.Khoddam.Rapid determination of metformin in human plasma using ion-pair HPLC.J Pharma Biomed Anal,2003,31(1):197-200.
8[1]Dunn CJ, Peters DH. Metformin: a review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus[ J]. Drugs, 1995,49(5) :721 - 749.
9[2]Brohon J, Noel M. Determination of metformin in plasma at therapeutic levels by gas-liquid chromatography using a nitrogen detector[J]. J Chromatogr, 1978,146(1): 148 - 151.
10[3]Keal J, Somogyi A. Rapid and sensitive high-performance liquid chromatographic assay for metformin in plasma and urine using ion-pair extraction techniques [ J ]. J Chromatogr B, 1986, 378(2) :503 - 508.
7Florentin,Tachea,Yumenal. HPLC-DAD Determination of Metformin in Human Plasma Using Derivatizationwit h P-Nit robenzoyl Chloride in A Biphasic System[J] . J Microchem,2001,68(1):13-19.
8ZHANG M,MOORE GA,L EVER M. Rapid and Simple High Performance Liquid Chromatographic Assay for t he Determination of Metformin in Human Plasma and Breast Milk [J] . J.Chromatogr, 2002,766(1 ):175-179.
