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骨髓增生异常综合征造血细胞凋亡增加的研究进展 被引量:2

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摘要 骨髓增生异常综合征(myelodys plastic syndrome,MDS)是一组造血干细胞恶性克隆性疾病。法美英(FAB)协作组将MDS分为5个亚型,即难治性贫血(RA)、环形铁粒幼细胞性难治性贫血(RAS)、难治性贫血伴原始细胞增多(RAEB)、难治性贫血伴原始细胞增多一转变型(RAEB—T)、慢性粒一单核细胞白血病(CMML)。1993年Yoshida等提出凋亡可能与MDS无效造血有关的假设后,国内外学者进行了大量研究,表明过度的骨髓造血细胞凋亡可能是MDS患者无效造血的主要原因。本文就MDS造血细胞凋亡增加作一综述。
出处 《浙江医学》 CAS 2007年第11期1241-1243,共3页 Zhejiang Medical Journal
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