摘要
目的评价黄芪注射液治疗噻氯匹定引起的白细胞减少症的临床疗效和安全性。方法51例噻氯匹定引起的白细胞减少症患者随机分为A、B两组,A组(26例):利血生20mg,每天3次;鲨肝醇100 mg,每天3次,连用4周。B组(25例):在A组治疗的基础上,应用黄芪注射液40ml加入250ml葡萄糖或生理盐水中静滴,每天1次,连用30天。观察两组患者用药前后外周血白细胞计数的变化。结果两组有效率分别为69.23%和96.00%,差异有统计学意义(P<0.05),均未见明显的副反应。结论黄芪注射液治疗噻氯匹定引起的白细胞减少症有显著疗效,且无明显的副反应。
Objective ： To assess the clinical effect and security of Astragalus Membranaceus Injection （AMI） in leucopenia patients induced by ticlopidine. Methods： 51 leucopenia patients were randomly assigned to AMI group（ n = 25, AMI 40 ml and 250 ml glucose or saline solution per day besides leucogen 20rag and batyl alcohol 100rag for 30 days） or control group（ n = 26 ,leucogen 20rag and batyl alcohol 100mg t. i. d for 4 weeks） . Contrast the white blood cell variety. Results： Effective rate was 69.23% vs 96.00% （P 〈 0.05）and none of side effect was found in both groups, Conclusion： Leucopenia patients induced by ticlopidine can be treated with AM/effectively without side effect.
出处
《泰山医学院学报》
CAS
2007年第9期706-707,共2页
Journal of Taishan Medical College
关键词
噻氯匹定
白细胞减少症
黄芪注射液
ticlopidine
leucopenia
Astragalus Membranacenus Injection
