摘要
目的观察小脑顶核电刺激(FNS)结合康复治疗血管性痴呆的临床疗效。方法血管性痴呆患者63例,随机分为FNS组40例和对照组23例。FNS组采用小脑顶核电刺激结合康复治疗;对照组仅采用康复治疗。认知功能采用简易智力量表(MMSE)、日常生活能力采用Barthel指数(BI)评定,经颅多普勒超声(TCD)监测治疗前后脑血流速度。结果FNS组MMSE、BI评分提高(P<0.05),临床有效率95%。治疗前后脑血流明显改善(P<0.01)。结论FNS可改善血管性痴呆患者认知功能和日常生活能力,可能与脑血流改善有关。
Objective To observe the effects of fastigial nucleus stimulation （FNS） combined with rehabilitation on vascular dementia. Methods 63 vascular dementia patients were randomly divided into FNS group （40 patients） and control group （23 patients）. Patients in the FNS group were treated with FNS and rehabilitation therapy, while those in the control group were treated with rehabilitation therapy only. Cognitive function were evaluated with Mini-Mental State Examination （MMSE）, activities of daily living （ADL） were evaluated with Barthel Index（BI）, cerebral blood flow velocity before and after therapy was detected with transcranial Doppler （TCD）. Results The scales of MMSE and BI increased significantly; the clinical efficieney was 95%. Cerebral blood flow velocity after therapy improved significantly （P〈0.01）. Conclusion FNS can improve the cognitive function and ADL in vascular dementia patients, that may be related with the improvement of cerebral blood flow.
出处
《中国康复理论与实践》
CSCD
2007年第11期1054-1055,共2页
Chinese Journal of Rehabilitation Theory and Practice
关键词
血管性痴呆
小脑顶核电刺激
脑血流
康复
vascular dementia
fastigial nucleus stimulation （FNS）
cerebral blood flow
rehabilitation
